RESEARCH

THE TONGUE

Detection

THE GANGLION

Connection

THE BRAIN

Perception

TOOLS

OUR TEAM

Hojoon Lee

Principal Investigator

Cook Hall 2-133

office: 847.491.5529

hojoon.lee [at] northwestern.edu

Jiahao Ye

Post-doc

jiahao.ye [at] northwestern.edu

Alex Pekerman

Lab Manager / Research Tech

Cook Hall 2-159

847.467.7895

alexpek [at] northwestern.edu

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Yue Yu

PhD Candidate

yueyu2023 [at] u.northwestern.edu

Gyujin Park

Post-doc

gyujin.park [at] northwestern.edu

Jasmine N Tran

Student

jasminetran2023[at] u.northwestern.edu

John Yun

Lab Technician

jonghwayun2020 [at] u.northwestern.edu

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Amanda Kalishman

Student

amandakalishman2022[at] u.northwestern.edu

Former Members

Hongjie Xia

Lab technician (2020)

currently PhD student at Boston University

Yoana Ivanova 

Student researcher

(2019-2020)

PUBLICATIONS

Lee, H., Macpherson, L.J., Parada, C.A., Zuker, C.S., and Ryba, N.J.P (2017) Rewiring the Taste System. Nature, 548:330-333.

*also read "Solving an identity crisis in the taste system." 

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Oury, F., Khrimian, L., Denny, C.A., Gardin, A., Chamouni, A., Goeden, N., Huang, Y., Lee, H., Srinivas, P. Gao, X.-B., Suyama, S., Langer, T., Mann, J.J., Horvath, T.L., Bonnin, A., and Karsenty, G. (2013) Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions. Cell, 155:228-241.

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Ploper, D., Lee, H.X., and De Robertis, E.M. (2011) Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Developmental Biology, 352:317-328.

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Lee, H.X., Mendes, F.A., Plouhinec, J.L., and De Robertis, E.M. (2009) Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes and Development, 23:2551-2562. 

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Fuentealba, L. C., Eivers, E., Lee, H. X., and De Robertis, E. M. (2009). Integration of BMP, RTK and Wnt Signaling through Smad1 Phosphorylations. The Handbook of Cell Signaling. Bradshaw R. and Dennis E. (Eds). Elsevier Inc, Second Edition.​

Ambrosio*, A. L., Taelman*, V. F., Lee*, H. X., Metzinger, C., Coffinier, C., and De Robertis, E. M. (2008). Crossveinless-2 is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. Developmental Cell, 15:248-260.  * co-first author 

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Lee, H. X., Ambrosio, A. L., Reversade, B., and De Robertis, E. M. (2006). Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell, 124:147-159. 

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Reversade, B., Kuroda, H., Lee, H., Mays, A., and De Robertis, E. M. (2005). Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development, 132:3381-3392. 

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Sun, W., Lee, H., Choe, Y., Cho, S., Kim, D.H., and Kim, K. (2001). Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones. Journal of Neuroendocrinology, 13:249-260. 

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Jung, N., Sun, W., Lee, H., Cho, S., Shim, C., and Kim, K., (1998). Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: differential involvement of c-fos and c-jun protooncogenes. Molecular Brain Research, 61:162-169. 

CONTACT

Mailing Address:
2205 Tech Drive

Hogan Hall 2-160
Evanston IL, 60208

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Lab Address:

2220 Campus Drive

Cook Hall 2-159
Evanston, IL 60208

(847) 467-7895

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