Hojoon Lee

Principal Investigator

Cook Hall 2-133

office: 847.491.5529

hojoon.lee [at] northwestern.edu

Jiahao Ye


jiahao.ye [at] northwestern.edu

Alex Pekerman

Lab Manager / Research Tech

Cook Hall 2-159


alexpek [at] northwestern.edu

Yue Yu

PhD Candidate

yueyu2023 [at] u.northwestern.edu

Gyujin Park


gyujin.park [at] northwestern.edu

Syed Uddin

PhD Student

SyedUddin2026 [at] u.northwestern.edu

Richard Hwang

PhD Student

richardhwang2026 [at] u.northwestern.edu

Jasmine N Tran


jasminetran2023[at] u.northwestern.edu

Amanda Kalishman


amandakalishman2022[at] u.northwestern.edu

Rowan Kramer-Mann 


rowankramer-mann2024 [at] u.northwestern.edu

Junhua Tan

Lab Technician

junhuatan2021 [at] u.northwestern.edu

Heather Birdsell 


heatherbirdsell2023 [at] u.northwestern.edu

Former Members

Hongjie Xia

Lab technician (2020)

currently PhD student at Boston University

Yoana Ivanova 

Student researcher


John Yun 

Lab Technician


Lee, H., Macpherson, L.J., Parada, C.A., Zuker, C.S., and Ryba, N.J.P (2017) Rewiring the Taste System. Nature, 548:330-333.

*also read "Solving an identity crisis in the taste system.

Oury, F., Khrimian, L., Denny, C.A., Gardin, A., Chamouni, A., Goeden, N., Huang, Y., Lee, H., Srinivas, P. Gao, X.-B., Suyama, S., Langer, T., Mann, J.J., Horvath, T.L., Bonnin, A., and Karsenty, G. (2013) Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions. Cell, 155:228-241.

Ploper, D., Lee, H.X., and De Robertis, E.M. (2011) Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Developmental Biology, 352:317-328.

Lee, H.X., Mendes, F.A., Plouhinec, J.L., and De Robertis, E.M. (2009) Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes and Development, 23:2551-2562. 

Fuentealba, L. C., Eivers, E., Lee, H. X., and De Robertis, E. M. (2009). Integration of BMP, RTK and Wnt Signaling through Smad1 Phosphorylations. The Handbook of Cell Signaling. Bradshaw R. and Dennis E. (Eds). Elsevier Inc, Second Edition.​

Ambrosio*, A. L., Taelman*, V. F., Lee*, H. X., Metzinger, C., Coffinier, C., and De Robertis, E. M. (2008). Crossveinless-2 is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. Developmental Cell, 15:248-260.  * co-first author 

Lee, H. X., Ambrosio, A. L., Reversade, B., and De Robertis, E. M. (2006). Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell, 124:147-159. 

Reversade, B., Kuroda, H., Lee, H., Mays, A., and De Robertis, E. M. (2005). Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development, 132:3381-3392. 

Sun, W., Lee, H., Choe, Y., Cho, S., Kim, D.H., and Kim, K. (2001). Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones. Journal of Neuroendocrinology, 13:249-260. 

Jung, N., Sun, W., Lee, H., Cho, S., Shim, C., and Kim, K., (1998). Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: differential involvement of c-fos and c-jun protooncogenes. Molecular Brain Research, 61:162-169. 


Mailing Address:
2205 Tech Drive

Hogan Hall 2-160
Evanston IL, 60208

Lab Address:

2220 Campus Drive

Cook Hall 2-159
Evanston, IL 60208

(847) 467-7895



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