RESEARCH

THE TONGUE

Detection

THE GANGLION

Connection

THE BRAIN

Perception

TOOLS

PUBLICATIONS

Lee, H., Macpherson, L.J., Parada, C.A., Zuker, C.S., and Ryba, N.J.P (2017) Rewiring the Taste System. Nature, 548:330-333.

*also read "Solving an identity crisis in the taste system." 

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Oury, F., Khrimian, L., Denny, C.A., Gardin, A., Chamouni, A., Goeden, N., Huang, Y., Lee, H., Srinivas, P. Gao, X.-B., Suyama, S., Langer, T., Mann, J.J., Horvath, T.L., Bonnin, A., and Karsenty, G. (2013) Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions. Cell, 155:228-241.

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Ploper, D., Lee, H.X., and De Robertis, E.M. (2011) Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Developmental Biology, 352:317-328.

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Lee, H.X., Mendes, F.A., Plouhinec, J.L., and De Robertis, E.M. (2009) Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes and Development, 23:2551-2562. 

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Fuentealba, L. C., Eivers, E., Lee, H. X., and De Robertis, E. M. (2009). Integration of BMP, RTK and Wnt Signaling through Smad1 Phosphorylations. The Handbook of Cell Signaling. Bradshaw R. and Dennis E. (Eds). Elsevier Inc, Second Edition.​

Ambrosio*, A. L., Taelman*, V. F., Lee*, H. X., Metzinger, C., Coffinier, C., and De Robertis, E. M. (2008). Crossveinless-2 is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. Developmental Cell, 15:248-260.  * co-first author 

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Lee, H. X., Ambrosio, A. L., Reversade, B., and De Robertis, E. M. (2006). Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell, 124:147-159. 

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Reversade, B., Kuroda, H., Lee, H., Mays, A., and De Robertis, E. M. (2005). Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development, 132:3381-3392. 

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Sun, W., Lee, H., Choe, Y., Cho, S., Kim, D.H., and Kim, K. (2001). Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones. Journal of Neuroendocrinology, 13:249-260. 

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Jung, N., Sun, W., Lee, H., Cho, S., Shim, C., and Kim, K., (1998). Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: differential involvement of c-fos and c-jun protooncogenes. Molecular Brain Research, 61:162-169.