Department of Neurobiology

the Lee Lab

How We Taste Things

RESEARCH

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TOOLS

OUR TEAM

Principal Investigator

Cook Hall 2-133

office: 847.491.5529

hojoon.lee [at] northwestern.edu

Research Technician

hongjie.xia [at] northwestern.edu

Student

yoanaivanova2021 [at] u.northwestern.edu

Lab Manager / Research Tech

Cook Hall 2-159

847.467.7895

alexpek [at] northwestern.edu

Student

jonghwayun2020 [at] u.northwestern.edu

Post-doc

Cook Hall 2-159

847.467.7895

jiahao.ye [at] northwestern.edu

PhD Candidate

Cook Hall 2-159

yueyu2023 [at] u.northwestern.edu

PUBLICATIONS

Lee, H., Macpherson, L.J., Parada, C.A., Zuker, C.S., and Ryba, N.J.P (2017) Rewiring the Taste System. Nature, 548:330-333.

*also read "Solving an identity crisis in the taste system."

Oury, F., Khrimian, L., Denny, C.A., Gardin, A., Chamouni, A., Goeden, N., Huang, Y., Lee, H., Srinivas, P. Gao, X.-B., Suyama, S., Langer, T., Mann, J.J., Horvath, T.L., Bonnin, A., and Karsenty, G. (2013) Maternal and Offspring Pools of Osteocalcin Influence Brain Development and Functions. Cell, 155:228-241.

Ploper, D., Lee, H.X., and De Robertis, E.M. (2011) Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases. Developmental Biology, 352:317-328.

Lee, H.X., Mendes, F.A., Plouhinec, J.L., and De Robertis, E.M. (2009) Enzymatic regulation of pattern: BMP4 binds CUB domains of Tolloids and inhibits proteinase activity. Genes and Development, 23:2551-2562.

Fuentealba, L. C., Eivers, E., Lee, H. X., and De Robertis, E. M. (2009). Integration of BMP, RTK and Wnt Signaling through Smad1 Phosphorylations. The Handbook of Cell Signaling. Bradshaw R. and Dennis E. (Eds). Elsevier Inc, Second Edition.

Ambrosio, A. L., Taelman, V. F., Lee, H. X., Metzinger, C., Coffinier, C., and De Robertis, E. M. (2008). Crossveinless-2 is a BMP feedback inhibitor that binds Chordin/BMP to regulate Xenopus embryonic patterning. Developmental Cell, 15:248-260. co-first author

Lee, H. X., Ambrosio, A. L., Reversade, B., and De Robertis, E. M. (2006). Embryonic dorsal-ventral signaling: secreted frizzled-related proteins as inhibitors of tolloid proteinases. Cell, 124:147-159.

Reversade, B., Kuroda, H., Lee, H., Mays, A., and De Robertis, E. M. (2005). Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development, 132:3381-3392.

Sun, W., Lee, H., Choe, Y., Cho, S., Kim, D.H., and Kim, K. (2001). Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones. Journal of Neuroendocrinology, 13:249-260.

Jung, N., Sun, W., Lee, H., Cho, S., Shim, C., and Kim, K., (1998). Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: differential involvement of c-fos and c-jun protooncogenes. Molecular Brain Research, 61:162-169.

CONTACT

Mailing Address:
2205 Tech Drive

Hogan Hall 2-160
Evanston IL, 60208

Lab Address:

2220 Campus Drive

Cook Hall 2-159
Evanston, IL 60208

(847) 467-7895

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